Monkeypox Cases Rising: How Worried Should You Be

Mpox has been a public health problem in parts of Africa for decades

New Delhi:
The World Health Organization has declared that an outbreak of mpox, a viral infection that spreads through close contact, represents a global health emergency for the second time in two years. Mpox causes flu-like symptoms and pus-filled lesions.

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While usually mild, mpox can kill. Children, pregnant women and people with weakened immune systems, such as those with HIV, are all at higher risk of complications. The WHO declared the recent outbreak of the disease a public health emergency after a new offshoot of the mpox virus, first identified in Democratic Republic of Congo, began spreading to other neighbouring countries.
Mpox transmits through close physical contact, including sexual contact, but there is no evidence that it spreads easily through the air. The new offshoot has caused global alarm because it appears to spread more easily between people.
Two years ago, the WHO declared mpox was an emergency when a form of the disease, ‘clade IIb’, began to spread globally, largely among men who have sex with men. That outbreak was brought under control after behaviour change and safe sex practices, plus vaccines, helped people at risk protect themselves in many countries.
But mpox has been a public health problem in parts of Africa for decades. The first ever human case was in Congo in 1970, and it has had outbreaks ever since. The current outbreak, Congo’s worst ever, has seen 27,000 cases and more than 1,100 deaths since January 2023, largely among children.
Two strains of mpox are now spreading in Congo – the endemic form of the virus, ‘clade I’, and a new offshoot called ‘clade Ib’, with the term ‘clade’ referring to a form of the virus. The new offshoot has now moved from eastern Congo to Rwanda, Uganda, Burundi and Kenya.
Sweden reported the first case of the new form, ‘clade Ib’, outside Africa on Thursday. A WHO spokesperson said the case reiterated the need for partnership, and the agency continues to advise against travel restrictions to stop the spread of mpox. Pakistan on Friday also confirmed a case of the mpox virus in a patient who had returned from a Gulf country, though it was unclear whether it was of the new variant or of the clade that has been spreading globally since 2022.
But in 2022, a WHO appeal for $34 million to fight mpox got no take-up from donors, and there was huge inequity in who had access to vaccine doses. African countries had no access to the two shots used in the global outbreak, made by Bavarian Nordic and KM Biologics.
Two years later that remains the case, although there are efforts to change that, the WHO said on Wednesday as it appealed for dose donations from countries with stockpiles. Africa CDC said it has a plan to secure doses, without elaborating further, but stocks are currently limited.
Fatality rates vary, and depend heavily on the healthcare available to the sickest patients. In Congo in this outbreak, the rate across both ‘clade I’ and ‘clade Ib’ has been around 4 per cent. ‘Clade II’, which spread globally, was much less deadly.
However, mpox is not COVID-19. There are tools that are proven to work to stop the spread and help those at risk, and it does not spread as easily. The challenge now, which the emergency declarations aim to highlight, is making sure those tools reach those who need them most, in Congo and neighbouring countries.