#image_title
Adolescents may experience delayed bipolar disorder (BD) progression after major depressive disorder (MDD) diagnosis, according to a study published online May 29 in JAMA Psychiatry.
Adrian E. Desai Boström, M.D., Ph.D., from the Karolinska Institute in Stockholm, and colleagues examined the association of age at MDD onset with early transition to BD and the subsequent use of psychiatric inpatient services as a severity indicator. The analysis included 114 adults and 114 youths participating in the Stockholm MDD Cohort (1997 to 2018), which encompassed both outpatient and inpatient care.
The researchers found that youth were substantially less likely to transition early (odds ratio, 0.42), despite having more outpatient visits (mean visits per month, 1.21 versus 0.97 for adults). Following a BD diagnosis, both groups experienced substantially reduced inpatient care, concurring with a marked decline in antidepressant use without increased lithium use.
“These results underscore the vital importance of early and accurate BD diagnosis in youths, especially in inpatient settings, and offer crucial insights for tailoring pharmacologic strategies in patients experiencing a first episode of MDD at risk for transitioning to BD,” the authors write.
Two authors disclosed ties to Janssen Sweden.
More information:
Adrian E. Desai Boström et al, Adolescent and Adult Transitions From Major Depressive Disorder to Bipolar Disorder, JAMA Psychiatry (2024). DOI: 10.1001/jamapsychiatry.2024.1133
© 2024 HealthDay. All rights reserved.
Citation:
Teens may experience delays in bipolar progression after major depressive disorder, according to study (2024, June 1)
retrieved 1 June 2024
from https://medicalxpress.com/news/2024-05-teens-delays-bipolar-major-depressive.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.
Canada's Denis Shapovalov is off to the third round of Wimbledon following a hard-fought 7-6…
Imagine the ultimate KFC snack. Can you picture it? Can you almost smell it? Well,…
United States President Joe Biden has dismissed speculations that he is considering withdrawing from the…
Gilas Pilipinas’ Justin Brownlee puts on another sensational game against Georgia to help secure the…
President Biden will speak with Israeli Prime Minister Benjamin Netanyahu via phone on Thursday following Hamas’…
Over 400 million years ago, an upwelling of hot rock from Earth's mantle wrenched apart…
This website uses cookies.